Objective To develop an intravenous thrombolysis nursing guideline for acute ischemic stroke as a guiding tool for the implementation of intravenous thrombolysis for acute ischemic stroke，and to provide a reference for the practice and management of nursing in the standardization of thrombolytic therapy. Methods According to the method of evidence-based nursing practice guidelines，the draft of intravenous thrombolysis nursing guidelines for acute ischemic stroke was constructed. The draft guidelines were reviewed by experts using the catalogue of Clinical Guidelines Research and Evaluation System Ⅱ. According to the results and suggestions of expert review，the guidelines were modified to form the formal guidelines. Results The recommendations included 5 aspects，namely hospital organization management，disease observation，observation and treatment of complications，posture and bed-leaving activities，and quality management. Conclusion The guidelines for intravenous thrombolysis nursing in acute ischemic stroke are evidence-based guidelines based on the best evidence，clinical practice and the judgment of professionals，and can be used as a practical basis for clinical medical staff to make scientific decisions on intravenous thrombolysis therapy in patients with acute ischemic stroke.

Objective To develop “clinical practice guideline（CPG） for nursing management of iodinated contrast media extravasation（ICME）” and to provide a reference for reducing the incidence and standardizing the management of ICME. Methods The CPG for nursing management of ICME strictly followed the method of developing evidence-based nursing practice guideline. The draft of this CPG was appraised according to Appraisal of Guidelines Research and Evaluation Ⅱ（AGREE Ⅱ）,and then it was finalized based on the results and suggestions of expert reviews. Results Recommendations for the constructed CPG included 4 aspects of risk factors,prevention methods,management principles,and quality improvement in ICME. Conclusion The “CPG for nursing management of ICME” was an evidence-based guideline based on the best evidence,Chinese clinical reality,and professional judg-ment,and it can provide practice bases for scientific clinical decision making by radiology and clinical medical staff.

Objective To develop evidence-based clinical practice guideline（CPG） for multiple myeloma patients,and to provide references for improving clinical practice and promote the clinical outcome of patients. Methods Based on the theoretical framework of JBI evidence-based health care model,this guideline was formulated strictly in accordance with the methodology of developing evidence-based CPG. After a draft guideline was developed,it was appraised according to AGREE（Appraisal of Guidelines Research and Evaluation） Instrument. Then the CPG was finalized based on evaluation results and the advice of experts. Results The recommendations of the CPG involved the care for patients with anemia and bleeding,kidney injury,bone injury,infection prevention,chemotherapy toxicity,hematopoietic stem cell transplantation,amyloidosis,hyperviscosity and so on. Conclusion This nursing practice guideline for multiple myeloma was constructed on the basis of best evidence,Chinese clinical practice and professional judgments,which can provide valuable references for nursing decision-making on multiple myeloma patients care.

Objective To establish a consensus of nursing experts on cognitive training nursing clinics. Methods Literatures at home and abroad were retrieved and key informant interviews were conducted. Expert Delphi mail questionnaire was developed according to the key issues of nursing care. Using 2 rounds of Delphi expert consultation and expert meetings,each item was revised and adjusted combined with the objective evidence and expert opinion. Results The experts reached a consensus on 4 dimensions of cognitive training nursing clinics：setup,contents,management,and personnel education,including 15 indicators. Conclusion The expert consensus on cognitive training nursing clinic was reliable and applicable,which can provide guidance for cognitive nursing clinics and promote regulated development of cognitive training.